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use React-typescript with custom typescript transformers (using typescript)

I have a typescript transformer I regularly use in the backend (Nodejs typescript), and I want to use it in the frontend too (React typescript). for that, I need to use typescript wrapper so the transformers will be enabled.

backend npm start command is npx ttsc frontend npm start command is react-scripts start

How can I use the ttsc command in the React app?

As for the record, the transformer used is a run-time type-checker, very useful!